Depot Vs. Oral Antipsychotic Efficacy

A recent paper has been published in JAMA Psychiatry. It compares the efficacy of different antipsychotic medications, and the route by which they’re given, and I believe it’s reserach that’s well-worth knowing about. If you would like to see the article first-hand, there is a link to it at the bottom of this page. However, there is a fabulous commentary and digest of it by Murtada Alsaif, blogging for the National Elf Service. Here is the link.

There are some important questions to ask yourself whilst reading this digest:

  • What makes the research such a convincing study?
  • How will it infulence what you advocate for the service users under your care?
  • What do the findings fail to consider?

If you would like more information about depot injections, please see my antipsychotic resource page.


Original article:

Tiihonen J et al. (2017) Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia. JAMA Psychiatry. 2017;74(7):686-693

Picture credits:
Syringe 1 With Drops (2008) by ZaldyImg. From Flikr.

Posted by Ben Murphy

Ben is a registered mental health nurse, holds an MSc in Genetic Counselling, and is a lecturer in Biological Sciences at City, University of London. Amongst other things, he teaches anatomy, physiology, pathophysiology and therapeutics to pre-reg. and post-reg. nursing students.

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